Introduction: Scientific evidence, along with other factors, can play an important role in policy decision making.Advanced analytics and mathematical models can produce such scientific evidence to inform policy decisions and mobilise action.The Imperial College COVID-19 Response Team (ICCRT) provided timely and robust epidemiological analysis essen
PURPOSE: This study aims to investigate whether there is a significant difference between typical and atypical parenchymal patterns in the development of fibrosis, which is the most crucial factor affecting morbidity in pulmonary sarcoidosis.METHODS: In our hospital, 145 cases with Siltzbach Types 2 and 3 sarcoidoses diagnosed by clinical, radiolog
BackgroundAlthough reduced glutathione (rGSH) is decreased in obese mice and humans, block of GSH synthesis by buthionine sulfoximine (BSO) results in a lean, insulin-sensitive phenotype.Data is lacking about the effect of BSO on GSH precursors, cysteine and glutamate.Plasma total cysteine (tCys) is positively associated with stearoyl-coenzyme A ST
Identification of pathways involved in the structural transitions of biomolecular systems is often complicated by the transient STAY ALERT nature of the conformations visited across energy barriers and the multiplicity of paths accessible in the multidimensional energy landscape.This task becomes even more challenging in exploring molecular systems
The mutated in colorectal cancer (MCC) gene is an important colorectal tumor suppressor gene, although few studies have reported the microRNA(s) that could directly target MCC in colorectal cancer.Here, we used microRNA (miRNA) Bondage and Fetish target prediction algorithms, and previously reported microarray data in human colorectal cancer found